With the arrival of spring, the increase in pollen concentrations such as grasses, olive, or plane trees marks the beginning of a critical stage for allergic patients. However, for many, conventional diagnosis based on global extracts is insufficient.
In current clinical practice, we find polysensitized patients: individuals who react simultaneously to multiple sources. In these cases, the key is not only knowing "what" one is allergic to, but identifying the specific protein that triggers the response.
What is the ISAC Test and how does it revolutionize diagnosis?
Unlike traditional allergy tests, the ISAC Test uses biochip technology to
simultaneously analyze 112 allergenic proteins from more than 50 different sources (pollen, mites, food, animal epithelia, etc.).
This approach is known as Component-Resolved Diagnosis (CRD). It allows dissecting the allergy at a molecular level, differentiating between the real components of a source and the proteins responsible for cross-reactions.
The importance of identifying the protein:
One of the greatest advantages of the ISAC Test is its ability to stratify risk. Within the same allergen (for example, peach or peanut), different proteins exist:
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Labile proteins: They usually cause mild and localized symptoms, such as itching in the mouth or throat.
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Stable proteins: They are resistant to heat and digestion. Their presence is associated with a significantly higher risk of severe systemic reactions or anaphylaxis.
Knowing exactly which molecule the patient is sensitive to allows the specialist to predict the severity of future reactions and take more rigorous preventive measures.
Who is this study indicated for?
The Test ISAC is the tool of choice in the following clinical scenarios:
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Polysensitized patients: When skin test results show multiple positivities and it is difficult to establish the primary cause.
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Inconclusive symptoms: When the patient's clinical history does not match the results of conventional tests.
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History of anaphylaxis: Cases of severe reactions of unknown or
idiopathic cause. -
Immunotherapy Optimization: Allows the allergist to design personalized vaccines with an exact protein composition for the patient's profile, drastically increasing the chances of treatment success.
Benefits of taking the test at Laboratorio Echevarne
As a reference center in clinical analysis, we guarantee a rigorous and professional process:
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Molecular Precision: A complete map of sensitivities in a single blood extraction.
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Agile Management: You can purchase your test online and go to any of our centers without the need for a prior appointment.
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Accessible Results: Within a period of 30 working days, you will receive your results directly in our online Patient Portal.
How to proceed
Taking the ISAC Test is a simple and safe process. We recommend going with an 8hour fast to any of our Laboratorio Echevarne centers with the proof of purchase or invoice. Once the report is obtained, it is essential to consult with a health professional for an adequate clinical interpretation and the design of a personalized action plan.
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Advanced Allergy Test (ISAC): Complete Map of 112 Allergens