Laboratorio de análisis Echevarne

Melatonin Curve Test

Melatonin Curve

The aim of this chronobiotic study is to evaluate the circadian rhythm of melatonin to identify states of chronodisruption.

Chronodisruption is a state of desynchronisation of different biological rhythms such as the wake-sleep rhythm or the rest-activity rhythm. Chronodisruption is associated with an increased risk of developing certain diseases or worsening of pre-existing pathologies.

What does it analyse?

It measures the concentration of melatonin in saliva at different times of the day (circadian phenotype) and compares it with the person’s chronotype, which is established by using different questionnaires to determine the amplitude and phase of the rhythm.

    Horne and Ostberg questionnaire: Assesses chronotype. PSQI questionnaire: Evaluates sleep quality.
    Epworth test: Measures degree of drowsiness. Sleep diary.
    Studies the lag in the melatonin curve with respect to the person’s chronotype (morning, intermediate or evening).

A detailed report on the circadian phenotype is generated. Personalised therapeutic guidelines are provided in order to synchronise the patient’s biological clock.

  • 512€
  • Sample:
  • Volume:
    0,5 ml
  • Storage of sample:
    5+/-3oC away from light
  • Turnaround time:
    14 working days
    (May vary)


Resynchronising the biological clock with exogenous melatonin helps improve the quality and latency of sleep by adjusting its phase. It also has beneficial effects on the evolution of different metabolic and inflammatory diseases, fibromyalgia, Parkinson’s, etc.

Which patients is it most useful for?

  • People with sleep disturbances due to changes in rhythm, or caused by shift work, jet-lag and/or other factors.
  • People with long-term stress, depression or professional burnout syndrome.
  • People who wish to proactively manage their health.
  • People with metabolic problems.

Otros Análisis Destacados

Consult your results