Toxicology and Bioanalysis
The main activity of the Toxicology and Bioanalysis unit is based on the use of advanced instrumental analysis techniques, such as mass spectrometry coupled to gas chromatography, liquid chromatography and ICP, using methods developed internally.
The areas of work are very varied: from the analysis of biomarkers of occupational exposure to chemical substances, therapeutic drug monitoring (TDM), confirmation of recreational drugs, determination of parameters in anti-ageing panels and tests related to nutrition (analysis of metals, vitamins, W3-W6 fatty acids...).
The unit also has extensive experience working with the pharmaceutical industry performing analytics for the development of drugs in its different clinical phases, both for humans and in the veterinary field.
Liquid chromatography (hplc and uhplc)
Coupled to tandem mass spectrometry (ms/ms)
- Analysis of recreational drugs in urine, saliva, hair and blood
- Bioanalysis for the pharmaceutical and veterinary industry (preclinical studies, bioequivalences, bioavailability studies, depletion studies...)
- Biomarkers of occupational exposure to chemicals
- Therapeutic drug monitoring (TDM)
- Analysis for the study of metabolopathies
UV, fluorescence or electrochemical detector
- Biomarkers of occupational exposure to chemicals
- Analysis of parameters of clinical interest: catecholamines, metanephrines and metabolites, porphyrins, pyridinoline/deoxypyridinoline, thiopurine methyltransferase...
- Therapeutic drug monitoring (TDM)
- Analysis for the study of metabolopathies
- Analysis of vitamins in samples of clinical interest
Gas chromatography
Mass detector
- Urine drug analysis
- Biomarkers of occupational exposure to chemicals
- Analysis for the study of metabolopathies
FID Detector, ECD
- Biomarkers of occupational exposure to chemicals
- Analysis of alcohol in blood and urine
- Intestinal permeability test
ICP-Mass
- Metals in biological samples
Infrared spectrophotometry
- Marked urea breath test
- Analysis of kidney and gall stones
UV-visible spectrophotometry
- Biomarkers of occupational exposure to chemicals
Fluorescence spectrophotometry
- Zinc protoporphyrin analysis
Electrometric techniques
- Analysis of fluorides, ionic calcium, carboxyhaemoglobin, methaemoglobin, pH
Other techniques
- Analysis of fats and proteins in faeces, reducing sugars
