Genetic Intolerance to Lactose and Fructose
The activity of lactase (the enzyme that metabolises lactose) decreases with age, meaning that 75% of the adult population has lactose intolerance of primary or genetic origin. This type of primary intolerance usually arises throughout life and has a genetic cause. People with this intolerance notice how consuming milk causes an increasing number of symptoms.
Hereditary fructose intolerance is a metabolic disease caused by mutations in the Aldolase B gene (ALDOB). These mutations cause an accumulation of fructose and a decrease in glucose, which are essential for many cellular functions. When a baby starts eating fruit, cereals or vegetables, sucrose breaks down and releases fructose and glucose. If the fructose cannot be metabolised properly, it starts to accumulate in the cells causing rapid symptoms of intolerance such as vomiting, lethargy or dehydration.
Which patients is it most useful for?
This test is suitable for the early detection of a possible primary intolerance to lactose and/or fructose as soon as a baby starts to eat different types of food.
- Turnaround time: 8 working days (Monday to Friday)
What does it analyse?
The test can detect genetic intolerance to lactose and fructose by means of a blood sample.